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Acne

Acne is one of the 10 most common conditions worldwide and its psychological impact is important, with reports of an increased risk of insomnia, depression, anxiety and attention deficit hyperactivity disorder and attention deficit hyperactivity disorder.


Acne pathogenesis is currently attributed to multiple factors, such as increased sebum production, altered sebum lipid quality, the proliferation of Propionibacterium acnes within the follicle and follicular hyperkeratinization. The increase in sebum excretion contributes to the development of acne. The neutral and polar lipids produced by the sebaceous glands play a variety of roles in signal transduction and are involved in biological pathways.

In addition, fatty acids act as nuclear receptor ligands such as PPARs (receptors activated by peroxisome proliferators). The lipids of the sebaceous gland have pro and anti-inflammatory properties, while the induction of the 5-lipoxygenase and cyclooxygenase-2 pathways in the sebocytes leads to the production of proinflammatory lipids. In addition, hormones such as androgens control the size of the sebaceous gland and the secretion of sebum. These events, following chains of reactions, lead to inframandibular inflammation, follicle rupture and peripollicular abscess formation, which stimulate the wound repair process.

Technologies

One of the techniques used for the treatment of acne is E.M.P.V., a vacuum massage causes structural changes that lead to improvement of acne symptoms.

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